Assuming average nucleosome spacing throughout the genome, how many molecules of histone H2A are present in the chromatin of one somatic human cell after DNA replication but before cell division?

Question

Chase Duncan

Biology

2 April, 19:21

Assuming average nucleosome spacing throughout the genome, how many molecules of histone H2A are present in the chromatin of one somatic human cell after DNA replication but before cell division?

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Answers (1)

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Harper Simon · Answer 1

Answer: Two molecules of H2A

Explanation:

Structural organization of nucleosomes were determined by isolating them from unfolded chromatin and it has been found that the basic units of chromatin are the nucleosomes which consist of histone octamers of two molecule each of histone H2A and other histone molecules like H2B, H3 and H4. The histones are wrapped around with 147bp of DNA in almost two (2) turns.