Which of the following is not true of homologous recombination? Only occurs between regions of DNA sharing >50 basepairs of nearly identical sequence. Can repair a collapsed replication fork. Always accompanied by some loss of DNA sequence. Responsible for crossing over at meiosis. Can repair a double-stranded break in chromosomal DNA.

Question

Brodie

Biology

8 October, 03:23

Which of the following is not true of homologous recombination? Only occurs between regions of DNA sharing >50 basepairs of nearly identical sequence. Can repair a collapsed replication fork. Always accompanied by some loss of DNA sequence. Responsible for crossing over at meiosis. Can repair a double-stranded break in chromosomal DNA.

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Leon Sloan · Answer 1

Recombination

Explanation:

Always accompanied by some loss of DNA sequence is not true of homologous recombination

Homologous recombination is a type of genetic recombination which requires homology between two DNA molecules Single stranded break occurs in same position of both DNA, after that strand invasion occurs Each invading strand joins to the broken end of other DNA molecule, creating a Holliday junction Holliday junction predicts cross over or non cross over recombinant DNA, depends on whether cleavage is on vertical or horizontal plane Cleavage in vertical plane produces cross over recombinant consisting of two heteroduplex DNA