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20 April, 10:39

What second messenger most directly causes calcium ions to be released from intracellular stores?

a. Diacylglycerol

b. Adenylyl cyclase inositol trisphosphate

c. Phospholipase A

d. Phospholipase C

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  1. 20 April, 10:44
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    Answer: adenylyl cyclase inositol triphosphate mainly known as IP3 causes the release of Calcium ions directly from the inracellular stores and causea contraction.

    Explanation:

    IP3, inositol phosphate is a second messenger a signaling molecule. It is made by hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2), a phospholipid that is located in the plasma membrane, by an enzyme phospholipase C.

    IP3 binds to the calcium channels and opens Ca2 + channels that are embedded in the ER membrane, releasing Ca2 + into the cytosol. Calcium ions released may cause contraction and regulate the Ca2 + channels in the membranes.
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