Definition of Krebs cycle

The sequence of reactions by which most living cells generate energy during the process of aerobic respiration. It takes place in the mitochondria, consuming oxygen, producing carbon dioxide and water as waste products, and converting ADP to energy-rich ATP.

The citric acid cycle - also known as the TCA cycle or the Krebs cycle - is a series of chemical reactions used by all aerobic organisms to release stored energy through the oxidation of acetyl-CoA derived from carbohydrates, fats, and proteins into adenosine triphosphate and carbon dioxide.