Which of the following would produce a silent mutation?

A. The deletion of a single base.

B. The replacement of a single base, producing a stop codon.

C. The replacement of a single base, producing the same amino acid.

D. The insertion of a single base.

C

Explanation:

A silent mutation is a mutation that does not have an observable change or effect on the organism bearing it. If a base in a DNA sequence changes but the new codon codes for the same amino acid (remember amino acids translation have redundancies), then they will be no observable effect. The most lethal kind of mutation is deletion and insertion because they result in a frameshift mutation.

C

Explanation:

a silent mutation is not one that can be seen or abserved in the phenotype