Drag the labels to show how the glucose and hormone levels will change in each mouse after they are joined by parabiosis. labels may be used once, more than once, or not at all. hints

Answer: Parabiosis is an effective way to evaluate hormone function because it permits the exchange of only long-lived molecules (such as hormones) between the two joined individuals. Thus, the glucose levels of each mouse will stay the same, but the hormone levels will not. The db mutant's hormone level will decrease, and the wild type's hormone level will increase. Coleman's goal was to determine if the ob and db genes function in the hormonal regulation of appetite and body fat. In this experiment, if both appetite-suppressing hormone and glucose were exchanged, it would be impossible to determine whether any weight changes in the mice were caused by the transfer of hormone or the transfer of glucose from one mouse to the other. For example, an increase in hormone level (and thus greater appetite suppression) could lead to weight loss, as could a decrease in glucose level. On the other hand, a decrease in hormone level or an increase in glucose level could lead to weight gain.