Outline the roles of double-stranded RNA (dsRNA) in eukaryotic gene regulation. Select all that apply. (A) dsRNA can inhibit gene expression by inhibition of transcription through heterochromatin formation. (B) dsRNA can inhibit gene expression by inhibition of translation. (C) dsRNA can inhibit gene expression by inhibition of replication. (D) dsRNA can inhibit gene expression by destruction of mRNA. (E) dsRNA can inhibit gene expression by destruction of rRNA. (F) dsRNA can inhibit gene expression by inhibition of transcription through inhibitor synthesis.

dsRNA can inhibit gene expression by inhibition of transcription through heterochromatin formation.

dsRNA can inhibit gene expression by destruction of mRNA.

dsRNA can inhibit gene expression by inhibition of translation.

Explanation:

Eukaryotic gene expression, ds rna plays an important role in expression.

Double stranded RNA regulate gene expression by a process called RNA interference. In this process, ds rna is broken into short fragments which:

may lead to nuclear modification and increase heterochromatin;

may destroy mRNA by binding to specific regions,

by modifying mRNA which inhibits translation.

By all these ways, ds rna can inhibit gene expressession.

So, Correct choices should be:

dsRNA can inhibit gene expression by inhibition of transcription through heterochromatin formation.

dsRNA can inhibit gene expression by destruction of mRNA.

dsRNA can inhibit gene expression by inhibition of translation.