Consider phosphofructokinase, which statement is true? Group of answer choices

None of the above.

High ATP inhibits the enzyme; fructose-2,6-bisphosphate activates the enzyme.

Low ATP activates the enzyme; fructose - 2,6-bisphosphate inhibits the enzyme.

High ATP activates the enzyme; fructose - 2,6-bisphosphate inhibits the enzyme.

Fructose - 2,6-bisphosphate and ATP inhibit the enzyme.

Question

Jackie

Chemistry

17 October, 19:32

Consider phosphofructokinase, which statement is true? Group of answer choices

None of the above.

High ATP inhibits the enzyme; fructose-2,6-bisphosphate activates the enzyme.

Low ATP activates the enzyme; fructose - 2,6-bisphosphate inhibits the enzyme.

High ATP activates the enzyme; fructose - 2,6-bisphosphate inhibits the enzyme.

Fructose - 2,6-bisphosphate and ATP inhibit the enzyme.

+5

Answers (1)

Know the Answer?

Konnor Carpenter · Answer 1

High ATP inhibits the enzyme; fructose-2,6-bisphosphate activates the enzyme.

Explanation:

PFK-1 inhibitors are ATP and Citrate which is an intermediate metabolite of the aerobic cycle while the activators responsible for reversing such inhibition caused by ATP are ADP, AMP and Fructose - 2,6-bisphosphate. The lats one is a powerful activator of PFK-1 but in the liver.