How did TWO of the following contribute to the reemergence of a two-party system in the period 1820-1840? Major political personalities, states' rights, economic issues.

It was the issue of state's rights that most directly contributed to the advent of a two party system in the 19th century, with the Democrats generally in favor of Southern state's rights and the Whigs in favor or more national unity. This of course was related to economic issues in the sense that the Democrats were defending slavery.