What restriction did Spain place on American trade? The Spanish closed New Orleans to American trade. The Spanish would allow Americans to buy only Spanish goods. The Spanish prohibited Americans from trading with Britain. The Spanish closed the West Indies to American trade.

The answer is The Spanish closed New Orleans to American trade.

They did this by blocking the Mississippi river for all American trades in 1784. This makes it really difficult for traders to move around their goods to the international markets, causing both delay in shipment time and higher distribution cost.