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29 August, 05:54

What is the difference between the normal hemoglobin and sickle cell hemoglobin?

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  1. 29 August, 07:37
    Answer: Sickle hemoglobin differs from normal hemoglobin by a single amino acid: valine replaces glutamate at position 6 on the surface of the beta chain. This creates a new hydrophobic spot (shown white) ... The polymerized hemoglobin distorts red blood cells into an abnormal sickle shape.
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