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14 December, 09:55

Nucleotides can be radiolabeled before they are incorporated into newly forming DNA and can be assayed to track their incorporation. In a pulse-chase experiment, a student-faculty research team introduced labeled thymine (T) nucleotides into a culture of dividing human cells. After a short time, they added large amounts of unlabeled T nucleotides. In which cell cycle phase would the labeled T nucleotides become incorporated into the DNA?

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Answers (2)
  1. 14 December, 09:57
    0
    The S phase

    Explanation:

    The cell cycle is divided into two major phases:

    The interphase The m Phase

    The interphase is further sub-divided into 4 phases:

    The G0 phase: a dormant phase The G1 phase: cell growth and development phase The S phase: DNA synthesis/replication and centrosome duplication phase The G2 phase: protein synthesis phase

    The labeled T nucleotides will become incorporated into the cell's DNA during the DNA synthesis/replication phase of the cell cycle. At this phases, the double helix DNA unzips and each strand serves as a template for the synthesis of new strands. Replication fork forms and nucleotides are added to the growing chain of newly synthesized strands.

    The correct answer is S phase.
  2. 14 December, 10:19
    0
    In the interphase (taking into account that cell cycle is divided into two parts), t nucleotides become incorporated into the DNA
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