Most of Texas's largest towns and cities are located in the

A. Post Oak Belt.

B. South Texas Plain.

C. Blackland Prairie.

D. Piney Woods.

The answer to this question is: D. piney woods

Piney woods is a forrest terrestrial eco-region that is located on the East part of the texas. This region held about 12 major cities in Texas and takes up to 140,900 km² of Texas' territory including East Texas, southern Arkansas, western Louisiana, and southeastern Oklahoma