The blank established a line that the settlers could not cross

A. Pontiac proclamation of 1763

B. Ottawa agreement of 1766

C. Pontiac war of 1761

D. Treaty of Paris of 1765

E. Royal proclamation of 1763

The Royal Proclamation of 1763 made it so settlers could not cross past the Appalachian Mountains so it would not create tension between the Natives and the French. This came after the Seven Years' War and benefited the British.